University of Southern California

Morsut Lab

USC Stem Cell

Synthetic morphogenesis

Biological systems are capable of generating very elaborate and robust patterns. The endogenous systems are hard to understand, because they are complicated by the presence of multiple factors that are difficult to disentangle. (Signaling pathways have multiple target genes, one signal can activate multiple cascades, etc.) To define a new way of studying tissue patterning, we use synthetic parts and computational models to develop and study the rules of morphogenesis from the bottom up.